Open AccessProtein homology detection by HMM–HMM comparison
Author(s) -
Johannes Söding
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti125
Subject(s) - hidden markov model , false positive paradox , sequence alignment , pairwise comparison , multiple sequence alignment , homology (biology) , protein function prediction , smith–waterman algorithm , pattern recognition (psychology) , homology modeling , computer science , artificial intelligence , computational biology , genetics , biology , peptide sequence , protein function , gene , biochemistry , enzyme
Protein homology detection and sequence alignment are at the basis of protein structure prediction, function prediction and evolution.
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