Open AccessRecovering haplotype structure through recombination and gene conversion
Author(s) -
Mathieu Lajoie,
Nadia El-Mabrouk
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti1128
Subject(s) - haplotype , recombination , gene conversion , genetics , gene , computational biology , computer science , biology , allele
Understanding haplotype evolution subject to mutation, recombination and gene conversion is fundamental to understand genetic specificities of human populations and hereditary bases of complex disorders. The goal of this project is to develop new algorithmic tools assisting the reconstruction of historical relationships between haplotypes and the inference of haplotypes from genotypes.
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