Predicting gene function through systematic analysis and quality assessment of high-throughput data
Author(s) -
Patrick Kemmeren,
Thessa T. J. P. Kockelkorn,
Theo Bijma,
Rogier Donders,
Frank C. P. Holstege
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti103
Subject(s) - computer science , scalability , throughput , data mining , function (biology) , computational biology , genomics , genome , functional genomics , gene , biology , genetics , database , telecommunications , wireless
Determining gene function is an important challenge arising from the availability of whole genome sequences. Until recently, approaches based on sequence homology were the only high-throughput method for predicting gene function. Use of high-throughput generated experimental data sets for determining gene function has been limited for several reasons.
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