Kernel methods for predicting protein-protein interactions
Author(s) -
Asa BenHur,
William Stafford Noble
Publication year - 2005
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti1016
Subject(s) - computer science , pairwise comparison , false positive paradox , kernel (algebra) , kernel method , classifier (uml) , protein–protein interaction , artificial intelligence , machine learning , protein sequencing , support vector machine , data mining , pattern recognition (psychology) , computational biology , peptide sequence , biology , mathematics , gene , genetics , combinatorics
Despite advances in high-throughput methods for discovering protein-protein interactions, the interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experimentalists in the search for novel interactions.
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