PDZBase: a protein–protein interaction database for PDZ-domains | Zendy

Thijs Beuming | Zendy; Lucy Skrabanek | Zendy; Masha Y. Niv | Zendy; Piali Mukherjee | Zendy; Harel Weinstein | Zendy

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PDZBase: a protein–protein interaction database for PDZ-domains

Author(s) -

Thijs Beuming,

Lucy Skrabanek,

Masha Y. Niv,

Piali Mukherjee,

Harel Weinstein

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti098

Subject(s) - pdz domain , computer science , schematic , computational biology , protein–protein interaction , protein structure database , domain (mathematical analysis) , database , information retrieval , sequence database , biology , genetics , gene , mathematics , mathematical analysis , electronic engineering , engineering

PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from > 200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes).

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