Clustering of gene expression data using a local shape-based similarity measure
Author(s) -
Rajarajeswari Balasubramaniyan,
Eyke Hüllermeier,
Nils Weskamp,
Jörg Kämper
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti095
Subject(s) - cluster analysis , measure (data warehouse) , similarity (geometry) , similarity measure , computer science , data mining , expression (computer science) , pattern recognition (psychology) , gene expression , computational biology , artificial intelligence , gene , biology , genetics , image (mathematics) , programming language
Microarray technology enables the study of gene expression in large scale. The application of methods for data analysis then allows for grouping genes that show a similar expression profile and that are thus likely to be co-regulated. A relationship among genes at the biological level often presents itself by locally similar and potentially time-shifted patterns in their expression profiles.
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