Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites
Author(s) -
Chiara Sabatti,
Lars Rohlin,
Kenneth Lange,
James C. Liao
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti083
Subject(s) - transcription factor , computer science , dna binding site , transcription (linguistics) , computational biology , factor (programming language) , binding site , artificial intelligence , genetics , biology , promoter , programming language , linguistics , gene , gene expression , philosophy
Gene expression arrays enable measurements of transcription values for a large number or all genes in the genome. In order to better interpret these results and to use them to reconstruct transcription networks, information on location of binding sites for regulatory proteins in the entire genome is needed. In particular, this represents an open problem in Escherichia coli.
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