Improving promoter prediction Improving promoter prediction for the NNPP2.2 algorithm: a case study using Escherichia coli DNA sequences
Author(s) -
Sandy Burden,
YanXia Lin,
R. Zhang
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti047
Subject(s) - promoter , false positive paradox , escherichia coli , computational biology , algorithm , gene , dna , coding (social sciences) , gene prediction , computer science , biology , genetics , artificial intelligence , mathematics , genome , gene expression , statistics
Although a great deal of research has been undertaken in the area of promoter prediction, prediction techniques are still not fully developed. Many algorithms tend to exhibit poor specificity, generating many false positives, or poor sensitivity. The neural network prediction program NNPP2.2 is one such example.
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