SPAAN: a software program for prediction of adhesins and adhesin-like proteins using neural networks
Author(s) -
Gaurav Sachdeva,
Kaushal Kumar,
Preti Jain,
Srinivasan Ramachandran
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bti028
Subject(s) - bacterial adhesin , glycoprotein , biology , artificial neural network , computational biology , computer science , microbiology and biotechnology , escherichia coli , gene , genetics , artificial intelligence
The adhesion of microbial pathogens to host cells is mediated by adhesins. Experimental methods used for characterizing adhesins are time-consuming and demand large resources. The availability of specialized software can rapidly aid experimenters in simplifying this problem. We have employed 105 compositional properties and artificial neural networks to develop SPAAN, which predicts the probability of a protein being an adhesin (Pad).
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