easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses | Zendy

Tom H. Lindner | Zendy; Katrin Hoffmann | Zendy

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easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses

Author(s) -

Tom H. Lindner,

Katrin Hoffmann

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bti009

Subject(s) - perl , computer science , linkage (software) , unix , point (geometry) , programming language , interface (matter) , graphical user interface , operating system , genetics , software , biology , mathematics , geometry , bubble , maximum bubble pressure method , gene

We have generated the program easyLINKAGE that combines automated setup and performance of linkage analyses and simulation under an easy to handle graphical user interface for Microsoft Windows 2000/XP and standard UNIX systems. The program package supports two-point linkage analyses (FastLink v4.1 and SPLink v1.09), multi-point linkage analyses [GENEHUNTER v2.1, GENEHUNTER-PLUS with the emendation by Kong and Cox v1.2 (allele sharing modelling)] and the simulation package SLINK v2.65, and provides genome-wide as well as chromosomal postscript plots of LOD scores, NPL scores, P-values and other parameters.

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