MCQTL: multi-allelic QTL mapping in multi-cross design | Zendy

Marie-Françoise Jourjon | Zendy; Sylvain Jasson | Zendy; Jacques Marcel | Zendy; Baba Ngom | Zendy; Brigitte Mangin | Zendy

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MCQTL: multi-allelic QTL mapping in multi-cross design

Author(s) -

Marie-Françoise Jourjon,

Sylvain Jasson,

Jacques Marcel,

Baba Ngom,

Brigitte Mangin

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth481

Subject(s) - quantitative trait locus , computer science , r package , inclusive composite interval mapping , permutation (music) , software , family based qtl mapping , diallel cross , data mining , genetics , biology , gene mapping , programming language , physics , botany , hybrid , gene , acoustics , chromosome

The aim of the MCQTL software package is to perform QTL mapping in multi-cross designs. It allows the analysis of the usual populations derived from inbred lines and can link the families by assuming that the QTL locations are the same in all of them. Moreover, a diallel modelling of the QTL genotypic effects is allowed in multiple related families. The implemented model is a linear regression model. A composite interval mapping and an iterative QTL mapping are implemented to deal with multiple QTL models. Marker cofactor selections by forward or backward stepwise methods are implemented as well as computation of threshold test value by permutation.

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