Simulating genetic networks made easy: network construction with simple building blocks | Zendy

Steven Vercruysse | Zendy; Martin Kuiper | Zendy

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Simulating genetic networks made easy: network construction with simple building blocks

Author(s) -

Steven Vercruysse,

Martin Kuiper

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth478

Subject(s) - simple (philosophy) , computer science , java , interface (matter) , genetic algorithm , piecewise linear function , programming language , differential (mechanical device) , piecewise , algorithm , simulation , operating system , mathematics , machine learning , physics , philosophy , geometry , epistemology , bubble , maximum bubble pressure method , mathematical analysis , thermodynamics

We present SIM-plex, a genetic network simulator with a very intuitive interface in which a user can easily specify interactions as simple 'if-then' statements. The simulator is based on the mathematical model of Piecewise Linear Differential Equations (PLDEs). With PLDEs, genetic interactions are approximated as acting in a switch-like manner.

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