A rapid method for computationally inferring transcriptome coverage and microarray sensitivity | Zendy

Antônio Reverter | Zendy; Sean McWilliam | Zendy; Wes Barris | Zendy; Brian P. Dalrymple | Zendy

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A rapid method for computationally inferring transcriptome coverage and microarray sensitivity

Author(s) -

Antônio Reverter,

Sean McWilliam,

Wes Barris,

Brian P. Dalrymple

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth472

Subject(s) - sensitivity (control systems) , transcriptome , computer science , microarray , microarray analysis techniques , computational biology , data mining , biology , genetics , gene , gene expression , engineering , electronic engineering

There are many different gene expression technologies, including cDNA and oligo-based microarrays, SAGE and MPSS. For each organism of interest, coverage of the transcriptome and the genome will be different. We address the question of what level of coverage is required to exploit the sensitivity of the different technologies, and what is the sensitivity of the different approaches in the experimental study.

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