A computational search for box C/D snoRNA genes in the Drosophila melanogaster genome | Zendy

Maria Carmela Accardo | Zendy; Ennio Giordano | Zendy; Sara Riccardo | Zendy; Filomena Anna Digilio | Zendy; Giovanni Iazzetti | Zendy; Raffaele Calogero | Zendy; Maria Furia | Zendy

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A computational search for box C/D snoRNA genes in the Drosophila melanogaster genome

Author(s) -

Maria Carmela Accardo,

Ennio Giordano,

Sara Riccardo,

Filomena Anna Digilio,

Giovanni Iazzetti,

Raffaele Calogero,

Maria Furia

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth394

Subject(s) - drosophila melanogaster , genome , biology , gene , small nucleolar rna , melanogaster , genetics , drosophila (subgenus) , computational biology , non coding rna , rna

In eukaryotes, the family of non-coding RNA genes includes a number of genes encoding small nucleolar RNAs (mainly C/D and H/ACA snoRNAs), which act as guides in the maturation or post-transcriptional modifications of target RNA molecules. Since in Drosophila melanogaster (Dm) only few examples of snoRNAs have been identified so far by cDNA libraries screening, integration of the molecular data with in silico identification of these types of genes could throw light on their organization in the Dm genome.

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