SAD—a normalized structural alignment database: improving sequence–structure alignments | Zendy

Brian D. Marsden | Zendy; Ruben Abagyan | Zendy

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SAD—a normalized structural alignment database: improving sequence–structure alignments

Author(s) -

Brian D. Marsden,

Ruben Abagyan

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth244

Subject(s) - computer science , sequence alignment , multiple sequence alignment , data mining , structural alignment , database , information retrieval , biology , peptide sequence , biochemistry , gene

We present a structural alignment database that is specifically targeted for use in derivation and optimization of sequence-structure alignment algorithms for homology modeling. We have paid attention to ensure that fold-space is properly sampled, that the structures involved in alignments are of significant resolution (better than 2.5 A) and the alignments are accurate and reliable.

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