Probabilistic representation of gene regulatory networks
Author(s) -
Linyong Mao,
Haluk Resat
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bth236
Subject(s) - representation (politics) , probabilistic logic , gene regulatory network , computer science , systems biology , biological network , gene , regulation of gene expression , computational biology , simple (philosophy) , expression (computer science) , software , simplicity , gene expression , biology , artificial intelligence , genetics , philosophy , epistemology , politics , political science , law , programming language
Recent experiments have established unambiguously that biological systems can have significant cell-to-cell variations in gene expression levels even in isogenic populations. Computational approaches to studying gene expression in cellular systems should capture such biological variations for a more realistic representation.
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