GeneCluster 2.0: an advanced toolset for bioarray analysis
Author(s) -
Michael Reich,
K. Ohm,
Miguel Angelo,
Pablo Tamayo,
Jill P. Mesirov
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bth138
Subject(s) - computer science , java , sort , cluster analysis , permutation (music) , software , data mining , class (philosophy) , visualization , variety (cybernetics) , machine learning , programming language , artificial intelligence , information retrieval , physics , acoustics
GeneCluster 2.0 is a software package for analyzing gene expression and other bioarray data, giving users a variety of methods to build and evaluate class predictors, visualize marker lists, cluster data and validate results. GeneCluster 2.0 greatly expands the data analysis capabilities of GeneCluster 1.0 by adding classification, class discovery and permutation test methods. It includes algorithms for building and testing supervised models using weighted voting and k-nearest neighbor algorithms, a module for systematically finding and evaluating clustering via self-organizing maps, and modules for marker gene selection and heat map visualization that allow users to view and sort samples and genes by many criteria. GeneCluster 2.0 is a stand-alone Java application and runs on any platform that supports the Java Runtime Environment version 1.3.1 or greater.
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