A graph theoretical approach for predicting common RNA secondary structure motifs including pseudoknots in unaligned sequences
Author(s) -
Yongmei Ji,
Xing Xu,
Gary D. Stormo
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bth131
Subject(s) - pseudoknot , computational biology , structural motif , rna , pairwise comparison , nucleic acid secondary structure , protein secondary structure , nucleic acid structure , biology , riboswitch , conserved sequence , graph , multiple sequence alignment , sequence alignment , computer science , algorithm , genetics , gene , theoretical computer science , non coding rna , artificial intelligence , peptide sequence , biochemistry
RNA structure motifs contained in mRNAs have been found to play important roles in regulating gene expression. However, identification of novel RNA regulatory motifs using computational methods has not been widely explored. Effective tools for predicting novel RNA regulatory motifs based on genomic sequences are needed.
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