Evaluating the predictability of conformational switching in RNA | Zendy

Björn Voß | Zendy; Carsten Meyer | Zendy; Robert Giegerich | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Evaluating the predictability of conformational switching in RNA

Author(s) -

Björn Voß,

Carsten Meyer,

Robert Giegerich

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth129

Subject(s) - rna , predictability , folding (dsp implementation) , computer science , computational biology , nucleic acid structure , nucleic acid secondary structure , function (biology) , algorithm , biological system , chemistry , biology , mathematics , biochemistry , gene , genetics , statistics , engineering , electrical engineering

There are various cases where the biological function of an RNA molecule involves a reversible change of conformation. paRNAss is a software approach to the prediction of such structural switching in RNA. It is based on three hypotheses about the secondary structure space of a switching RNA molecule that can be evaluated by RNA folding and structure comparison. In the positive case, the predicted structural switching must be verified experimentally.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research