Open AccessConserved RNA secondary structures in viral genomes: a survey
Author(s) -
Ivo L. Hofacker,
Peter F. Stadler,
Roman R. Stocsits
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bth108
Subject(s) - genome , rna , computational biology , nucleic acid secondary structure , biology , conserved sequence , genetics , virology , base sequence , dna , gene
The genomes of RNA viruses often carry conserved RNA structures that perform vital functions during the life cycle of the virus. Such structures can be detected using a combination of structure prediction and co-variation analysis. Here we present results from pilot studies on a variety of viral families performed during bioinformatics computer lab courses in past years.
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