TANDEM: matching proteins with tandem mass spectra | Zendy

Robertson Craig | Zendy; Ronald C. Beavis | Zendy

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TANDEM: matching proteins with tandem mass spectra

Author(s) -

Robertson Craig,

Ronald C. Beavis

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth092

Subject(s) - tandem , matching (statistics) , tandem repeat , tandem mass spectrometry , computer science , computational biology , chemistry , biology , genetics , mass spectrometry , chromatography , mathematics , genome , statistics , materials science , composite material , gene

Tandem mass spectra obtained from fragmenting peptide ions contain some peptide sequence specific information, but often there is not enough information to sequence the original peptide completely. Several proprietary software applications have been developed to attempt to match the spectra with a list of protein sequences that may contain the sequence of the peptide. The application TANDEM was written to provide the proteomics research community with a set of components that can be used to test new methods and algorithms for performing this type of sequence-to-data matching.

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