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2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis
Author(s) -
Jing Hua Zhao
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bth071
Subject(s) - linkage disequilibrium , haplotype , linkage (software) , heuristic , software , computer science , the internet , disequilibrium , missing data , genetic algorithm , computer program , maximum likelihood , genetics , biology , statistics , artificial intelligence , mathematics , machine learning , allele , world wide web , medicine , programming language , gene , ophthalmology
Computer programs are introduced which calculate pair-wise linkage disequilibrium statistics and conduct haplotype frequency estimation, including X chromosome data, and using a heuristic algorithm to handle multiple genetic markers and missing data.

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