Ontologizing gene-expression microarray data: characterizing clusters with Gene Ontology
Author(s) -
Peter N. Robinson,
Andreas Wollstein,
Ulrike Böhme,
Bradley J. Beattie
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bth040
Subject(s) - gene ontology , computer science , microarray databases , xml , java , microarray analysis techniques , ontology , gene , function (biology) , cluster (spacecraft) , gene cluster , computational biology , data mining , information retrieval , gene expression , biology , genetics , programming language , world wide web , philosophy , epistemology
An XML-based Java application is described that provides a function-oriented overview of the results of cluster analysis of gene-expression microarray data based on Gene Ontology terms and associations. The application generates one HTML page with listings of the frequencies of explicit and implicit Gene Ontology annotations for each cluster, and separate, linked pages with listings of explicit annotations for each gene in a cluster.
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