Multi-species comparative mapping in silico using the COMPASS strategy | Zendy

Lei Liu | Zendy; George Gong | Zendy; Yong Liu | Zendy; Shreedhar Natarajan | Zendy; Denis M. Larkin | Zendy; Annelie Everts-van der Wind | Zendy; Mark Rebeiz | Zendy; Jonathan E. Beever | Zendy

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Multi-species comparative mapping in silico using the COMPASS strategy

Author(s) -

Lei Liu,

George Gong,

Yong Liu,

Shreedhar Natarajan,

Denis M. Larkin,

Annelie Everts-van der Wind,

Mark Rebeiz,

Jonathan E. Beever

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bth018

Subject(s) - genome , comparative genomics , biology , synteny , reference genome , computational biology , ensembl , genome project , human genome , compass , genomics , sequence alignment , genetics , gene , peptide sequence , cartography , geography

The completion of human and mouse genome sequences provides a valuable resource for decoding other mammalian genomes. The comparative mapping by annotation and sequence similarity (COMPASS) strategy takes advantage of the resource and has been used in several genome-mapping projects. It uses existing comparative genome maps based on conserved regions to predict map locations of a sequence. An automated multiple-species COMPASS tool can facilitate in the genome sequencing effort and comparative genomics study of other mammalian species.

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