Gene specific siRNA selector | Zendy

Natasha Levenkova | Zendy; Qingjuan Gu | Zendy; John J. Rux | Zendy

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Gene specific siRNA selector

Author(s) -

Natasha Levenkova,

Qingjuan Gu,

John J. Rux

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg437

Subject(s) - small interfering rna , functional genomics , gene , computational biology , rna interference , gene expression , trans acting sirna , function (biology) , biology , rna , gene silencing , genomics , genetics , genome

Small interfering RNA (siRNA) is used in functional genomics applications to decrease the expression of a target gene, which may yield a biological effect that suggests a function for the target gene. The siRNA design tool scans a target gene for candidate siRNA sequences that satisfy user-adjustable rules. Selected candidates are then screened to identify those siRNA sequences that are specific to the gene of interest.

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