Rapid and sensitive dot-matrix methods for genome analysis | Zendy

Yue Huang | Zendy; Ling Zhang | Zendy

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Rapid and sensitive dot-matrix methods for genome analysis

Author(s) -

Yue Huang,

Ling Zhang

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg429

Subject(s) - dot matrix , computer science , genome , software , matrix (chemical analysis) , distance matrix , similarity (geometry) , algorithm , artificial intelligence , biology , genetics , image (mathematics) , computer graphics (images) , gene , materials science , composite material , programming language

Dot-matrix plots are widely used for similarity analysis of biological sequences. Many algorithms and computer software tools have been developed for this purpose. Though some of these tools have been reported to handle sequences of a few 100 kb, analysis of genome sequences with a length of >10 Mb on a microcomputer is still impractical due to long execution time and computer memory requirement.

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