Functional topology in a network of protein interactions
Author(s) -
Nataša Pržulj,
Dennis A. Wigle,
Igor Jurišica
Publication year - 2004
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btg415
Subject(s) - computational biology , computer science , network analysis , function (biology) , interaction network , construct (python library) , mutation , protein–protein interaction , network model , set (abstract data type) , biological network , biology , genetics , artificial intelligence , gene , computer network , physics , quantum mechanics , programming language
The building blocks of biological networks are individual protein-protein interactions (PPIs). The cumulative PPI data set in Saccharomyces cerevisiae now exceeds 78 000. Studying the network of these interactions will provide valuable insight into the inner workings of cells.
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