Minimal cut sets in biochemical reaction networks | Zendy

Steffen Klamt | Zendy; Ernst Dieter Gilles | Zendy

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Minimal cut sets in biochemical reaction networks

Author(s) -

Steffen Klamt,

Ernst Dieter Gilles

Publication year - 2004

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg395

Subject(s) - metabolic network , computer science , computation , robustness (evolution) , network analysis , biological network , set (abstract data type) , identification (biology) , theoretical computer science , computational biology , algorithm , biology , biochemistry , quantum mechanics , gene , programming language , physics , botany

Structural studies of metabolic networks yield deeper insight into topology, functionality and capabilities of the metabolisms of different organisms. Here, we address the analysis of potential failure modes in metabolic networks whose occurrence will render the network structurally incapable of performing certain functions. Such studies will help to identify crucial parts in the network structure and to find suitable targets for repressing undesired metabolic functions.

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