Algorithms for large-scale genotyping microarrays | Zendy

Weimin Liu | Zendy; Xiaojun Di | Zendy; Geoffrey Yang | Zendy; Hajime Matsuzaki | Zendy; Jing Huang | Zendy; Rui Mei | Zendy; Thomas B. Ryder | Zendy; Teresa Webster | Zendy; Shoulian Dong | Zendy; Guoying Liu | Zendy; Keith Jones | Zendy; Giulia C. Kennedy | Zendy; David Kulp | Zendy

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Algorithms for large-scale genotyping microarrays

Author(s) -

Weimin Liu,

Xiaojun Di,

Geoffrey Yang,

Hajime Matsuzaki,

Jing Huang,

Rui Mei,

Thomas B. Ryder,

Teresa Webster,

Shoulian Dong,

Guoying Liu,

Keith Jones,

Giulia C. Kennedy,

David Kulp

Publication year - 2003

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg332

Subject(s) - genotyping , dna microarray , single nucleotide polymorphism , computational biology , computer science , genetics , data mining , biology , genotype , gene , gene expression

Analysis of many thousands of single nucleotide polymorphisms (SNPs) across whole genome is crucial to efficiently map disease genes and understanding susceptibility to diseases, drug efficacy and side effects for different populations and individuals. High density oligonucleotide microarrays provide the possibility for such analysis with reasonable cost. Such analysis requires accurate, reliable methods for feature extraction, classification, statistical modeling and filtering.

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