RED-T: utilizing the Ratios of Evolutionary Distances for determination of alternative phylogenetic events
Author(s) -
Kamyar Farahi,
William B. Whitman,
Eileen Kraemer
Publication year - 2003
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btg284
Subject(s) - phylogenetic tree , phylogenetics , evolutionary biology , phylogenetic network , java , biology , mechanism (biology) , computer science , gene , genetics , physics , quantum mechanics , programming language
RED-T is a Java application for phylogenetic analysis based on a unique method, RED, that utilizes the ratios of evolutionary distances E(d) to distinguish between alternative evolutionary histories. RED-T allows the user to examine if any given experimental gene shares the same evolutionary history as the designated control gene(s). Moreover, the tool detects any differences in evolutionary history and allows the user to examine comparisons of E(d) for a likely explanation. Lateral gene transfer, which may have a significant influence in organismal evolution is one mechanism that could explain the findings of these RED-T analyses.
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