Identification and quantification of disease-related gene clusters
Author(s) -
Gábor Firneisz,
Idit Zehavi,
Csaba Vermes,
Anita Hanyecz,
Joshua A. Frieman,
Tibor T. Glant
Publication year - 2003
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btg252
Subject(s) - identification (biology) , computational biology , disease , gene , computer science , biology , genetics , medicine , pathology , botany
DNA microarray technology and the completion of human and mouse genome sequencing programs are now offering new avenues for the investigation of complex genetic diseases. In particular, this makes possible the study of the spatial distribution of disease-related genes within the genome. We report on the first systematic search for clustering of genes associated with a polygenic autoimmune disease.
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