Computational analysis of stop codon readthrough in D.melanogaster | Zendy

Misaki Sato | Zendy; Hitomi Umeki | Zendy; Rintaro Saito | Zendy; Akio Kanai | Zendy; Masaru Tomita | Zendy

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Computational analysis of stop codon readthrough in D.melanogaster

Author(s) -

Misaki Sato,

Hitomi Umeki,

Rintaro Saito,

Akio Kanai,

Masaru Tomita

Publication year - 2003

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg183

Subject(s) - stop codon , genbank , drosophila melanogaster , gene , genetics , computational biology , biology , untranslated region , translation (biology) , melanogaster , computer science , rna , messenger rna

Readthrough is an unusual process in which a stop codon is misread or skipped. Recently it has been shown that some translation is regulated by the readthrough reactions although the complete mechanism is not clear. Therefore, the discovery of 'readthrough genes' is important for further investigation of their cellular roles, which may provide additional insights into the mechanism of translational regulation.

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