Unsupervised feature selection via two-way ordering in gene expression analysis
Author(s) -
Chris Ding
Publication year - 2003
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btg149
Subject(s) - selection (genetic algorithm) , gene , feature selection , computer science , phenotype , set (abstract data type) , expression (computer science) , similarity (geometry) , computational biology , feature (linguistics) , gene selection , data mining , artificial intelligence , biology , gene expression , genetics , linguistics , philosophy , image (mathematics) , programming language , microarray analysis techniques
Selection of genes most relevant and informative for certain phenotypes is an important aspect in gene expression analysis. Most current methods select genes based on known phenotype information. However, certain set of genes may correspond to new phenotypes which are yet unknown, and it is important to develop novel effective selection methods for their discovery without using any prior phenotype information.
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