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A mathematical programming approach for gene selection and tissue classification
Author(s) -
Minghe Sun,
Momiao Xiong
Publication year - 2003
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btg145
Subject(s) - selection (genetic algorithm) , integer programming , computer science , gene selection , gene expression programming , genetic programming , data mining , variety (cybernetics) , parametric statistics , machine learning , parametric programming , artificial intelligence , microarray analysis techniques , algorithm , mathematics , gene , gene expression , biology , statistics , biochemistry
Extracting useful information from expression levels of thousands of genes generated with microarray technology needs a variety of analytical techniques. Mathematical programming approaches for classification analysis outperform parametric methods when the data depart from assumptions underlying these methods. Therefore, a mathematical programming approach is developed for gene selection and tissue classification using gene expression profiles.

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