Automatic analysis of DNA microarray images using mathematical morphology | Zendy

Jesús Angulo | Zendy; Jean Serra | Zendy

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Automatic analysis of DNA microarray images using mathematical morphology

Author(s) -

Jesús Angulo,

Jean Serra

Publication year - 2003

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg057

Subject(s) - mathematical morphology , morphology (biology) , dna , computational biology , computer science , dna microarray , artificial intelligence , pattern recognition (psychology) , biology , image processing , genetics , gene , image (mathematics) , gene expression

DNA microarrays are an experimental technology which consists in arrays of thousands of discrete DNA sequences that are printed on glass microscope slides. Image analysis is an important aspect of microarray experiments. The aim of this step is to reduce an image of spots into a table with a measure of the intensity for each spot. Efficient, accurate and automatic analysis of DNA spot images is essential in order to use this technology in laboratory routines.

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