Subnetwork hierarchies of biochemical pathways | Zendy

Petter Holme | Zendy; Mikael Huss | Zendy; Hawoong Jeong | Zendy

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Subnetwork hierarchies of biochemical pathways

Author(s) -

Petter Holme,

Mikael Huss,

Hawoong Jeong

Publication year - 2003

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btg033

Subject(s) - subnetwork , computer science , theoretical computer science , decomposition , graph , biological network , hierarchical organization , metabolic network , graph theory , core (optical fiber) , computational biology , data mining , biology , mathematics , computer network , ecology , telecommunications , management , combinatorics , economics

The vastness and complexity of the biochemical networks that have been mapped out by modern genomics calls for decomposition into subnetworks. Such networks can have inherent non-local features that require the global structure to be taken into account in the decomposition procedure. Furthermore, basic questions such as to what extent the network (graph theoretically) can be said to be built by distinct subnetworks are little studied.

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