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An information theoretic approach for analyzing temporal patterns of gene expression
Author(s) -
Jyotsna Kasturi,
Raj Acharya,
Murali Ramanathan
Publication year - 2003
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btg020
Subject(s) - cluster analysis , computer science , data mining , divergence (linguistics) , expression (computer science) , kullback–leibler divergence , hierarchical clustering , measure (data warehouse) , source code , matlab , software , pattern recognition (psychology) , artificial intelligence , programming language , philosophy , linguistics , operating system
Arrays allow measurements of the expression levels of thousands of mRNAs to be made simultaneously. The resulting data sets are information rich but require extensive mining to enhance their usefulness. Information theoretic methods are capable of assessing similarities and dissimilarities between data distributions and may be suited to the analysis of gene expression experiments. The purpose of this study was to investigate information theoretic data mining approaches to discover temporal patterns of gene expression from array-derived gene expression data.

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