The ENDS of assumptions: an online tool for the epistemic non-parametric drug–response scoring
Author(s) -
Ali Amiryousefi,
Bernardo Williams,
Mohieddin Jafari,
Jing Tang
Publication year - 2022
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btac217
Subject(s) - parametric statistics , computer science , sensitivity (control systems) , bayesian probability , drug , representation (politics) , parametric model , artificial intelligence , statistics , mathematics , medicine , pharmacology , political science , engineering , electronic engineering , politics , law
The drug sensitivity analysis is often elucidated from drug dose-response curves. These curves capture the degree of cell viability (or inhibition) over a range of induced drugs, often with parametric assumptions that are rarely validated.
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