The DOMINO web-server for active module identification analysis | Zendy

Hagai Levi | Zendy; Nima Rahmanian | Zendy; Ran Elkon | Zendy; Ron Shamir | Zendy

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The DOMINO web-server for active module identification analysis

Author(s) -

Hagai Levi,

Nima Rahmanian,

Ran Elkon,

Ron Shamir

Publication year - 2022

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btac067

Subject(s) - computer science , codebase , domino , identifier , identification (biology) , web server , key (lock) , source code , operating system , data mining , computer network , the internet , biology , biochemistry , botany , catalysis

Active module identification (AMI) is an essential step in many omics analyses. Such algorithms receive a gene network and a gene activity profile as input and report subnetworks that show significant over-representation of accrued activity signal ('active modules'). Such modules can point out key molecular processes in the analyzed biological conditions.

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