Nanopore base calling on the edge | Zendy

Peter Perešíni | Zendy; Vladimír Boža | Zendy; Broňa Brejová | Zendy; Tomáš Vinař | Zendy

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Nanopore base calling on the edge

Author(s) -

Peter Perešíni,

Vladimír Boža,

Broňa Brejová,

Tomáš Vinař

Publication year - 2021

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btab528

Subject(s) - bottleneck , computer science , nanopore sequencing , minion , base (topology) , convolutional neural network , exploit , computer hardware , embedded system , artificial intelligence , dna sequencing , computer security , dna , mathematical analysis , mathematics , biology , genetics

MinION is a portable nanopore sequencing device that can be easily operated in the field with features including monitoring of run progress and selective sequencing. To fully exploit these features, real-time base calling is required. Up to date, this has only been achieved at the cost of high computing requirements that pose limitations in terms of hardware availability in common laptops and energy consumption.

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