Open AccessFounder reconstruction enables scalable and seamless pangenomic analysis
Author(s) -
Tuukka Norri,
Bastien Cazaux,
Saska Dönges,
Daniel Valenzuela,
Veli Mäkinen
Publication year - 2021
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btab516
Subject(s) - computer science , scalability , software , programming language , operating system
Variant calling workflows that utilize a single reference sequence are the de facto standard elementary genomic analysis routine for resequencing projects. Various ways to enhance the reference with pangenomic information have been proposed, but scalability combined with seamless integration to existing workflows remains a challenge.
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