NaViA: a program for the visual analysis of complex mass spectra | Zendy

Daniel Quetschlich | Zendy; Tim K. Esser | Zendy; Thomas D. Newport | Zendy; Francesco Fiorentino | Zendy; Denis Shutin | Zendy; Siyun Chen | Zendy; Rachel E. Davis | Zendy; Silvia Lovera | Zendy; Idlir Liko | Zendy; Phillip J. Stansfeld | Zendy; Carol V. Robinson | Zendy

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NaViA: a program for the visual analysis of complex mass spectra

Author(s) -

Daniel Quetschlich,

Tim K. Esser,

Thomas D. Newport,

Francesco Fiorentino,

Denis Shutin,

Siyun Chen,

Rachel E. Davis,

Silvia Lovera,

Idlir Liko,

Phillip J. Stansfeld,

Carol V. Robinson

Publication year - 2021

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btab436

Subject(s) - mass spectrum , computer science , mass spectrometry , stoichiometry , spectral line , protein subunit , biological system , data mining , chemistry , biology , chromatography , physics , biochemistry , astronomy , gene

Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing the analysis of complex mixtures lead to an increasing diversity and complexity in the spectra obtained. These spectra can be time-consuming to tackle through manual assignment and challenging for automated approaches.

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