PuffAligner: a fast, efficient and accurate aligner based on the Pufferfish index | Zendy

Fatemeh Almodaresi | Zendy; Mohsen Zakeri | Zendy; Rob Patro | Zendy

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PuffAligner: a fast, efficient and accurate aligner based on the Pufferfish index

Author(s) -

Fatemeh Almodaresi,

Mohsen Zakeri,

Rob Patro

Publication year - 2021

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btab408

Subject(s) - computer science , software , data mining , metagenomics , profiling (computer programming) , index (typography) , algorithm , biology , world wide web , programming language , biochemistry , gene

Sequence alignment is one of the first steps in many modern genomic analyses, such as variant detection, transcript abundance estimation and metagenomic profiling. Unfortunately, it is often a computationally expensive procedure. As the quantity of data and wealth of different assays and applications continue to grow, the need for accurate and fast alignment tools that scale to large collections of reference sequences persists.

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