Visual exploration of large metabolic models
Author(s) -
Michael Aichem,
Tobias Czauderna,
Yan Zhu,
Jinxin Zhao,
Matthias Klapperstück,
Karsten Klein,
Jian Li,
Falk Schreiber
Publication year - 2021
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btab335
Subject(s) - computer science , visualization , source code , software , decomposition , domain (mathematical analysis) , metabolic network , code (set theory) , software visualization , data mining , software engineering , software system , computational biology , programming language , component based software engineering , biology , ecology , mathematical analysis , mathematics , set (abstract data type)
Large metabolic models, including genome-scale metabolic models, are nowadays common in systems biology, biotechnology and pharmacology. They typically contain thousands of metabolites and reactions and therefore methods for their automatic visualization and interactive exploration can facilitate a better understanding of these models.
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