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Umibato: estimation of time-varying microbial interaction using continuous-time regression hidden Markov model
Author(s) -
Shion Hosoda,
Tsukasa Fukunaga,
Michiaki Hamada
Publication year - 2021
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btab287
Subject(s) - computer science , python (programming language) , inference , hidden markov model , bayesian network , machine learning , regression , bayesian probability , artificial intelligence , regression analysis , data mining , conditional dependence , statistics , mathematics , operating system
Accumulating evidence has highlighted the importance of microbial interaction networks. Methods have been developed for estimating microbial interaction networks, of which the generalized Lotka-Volterra equation (gLVE)-based method can estimate a directed interaction network. The previous gLVE-based method for estimating microbial interaction networks did not consider time-varying interactions.

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