GSpace: an exact coalescence simulator of recombining genomes under isolation by distance | Zendy

Thimothée Virgoulay | Zendy; François Rousset | Zendy; Raphaël Leblois | Zendy

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GSpace: an exact coalescence simulator of recombining genomes under isolation by distance

Author(s) -

Thimothée Virgoulay,

François Rousset,

Raphaël Leblois

Publication year - 2021

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btab261

Subject(s) - coalescent theory , coalescence (physics) , computer science , software , inference , population , statistical inference , algorithm , biology , statistics , mathematics , artificial intelligence , programming language , genetics , demography , sociology , astrobiology , gene , phylogenetic tree

Simulation-based inference can bypass the limitations of statistical methods based on analytical approximations, but software allowing simulation of structured population genetic data without the classical n-coalescent approximations (such as those following from assuming large population size) are scarce or slow.

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