Differentially conserved amino acid positions may reflect differences in SARS-CoV-2 and SARS-CoV behaviour | Zendy

Denisa Bojková | Zendy; Jake E McGreig | Zendy; Katie-May McLaughlin | Zendy; Stuart G. Masterson | Zendy; Magdalena Antczak | Zendy; Marek Widera | Zendy; Verena Krähling | Zendy; Sandra Ciesek | Zendy; Mark N. Wass | Zendy; Martin Michaelis | Zendy; Jindřich Činátl | Zendy

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Differentially conserved amino acid positions may reflect differences in SARS-CoV-2 and SARS-CoV behaviour

Author(s) -

Denisa Bojková,

Jake E McGreig,

Katie-May McLaughlin,

Stuart G. Masterson,

Magdalena Antczak,

Marek Widera,

Verena Krähling,

Sandra Ciesek,

Mark N. Wass,

Martin Michaelis,

Jindřich Činátl

Publication year - 2021

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btab094

Subject(s) - covid-19 , virology , biology , virus , tropism , coronavirus , tmprss2 , in silico , viral entry , hek 293 cells , tissue tropism , betacoronavirus , cell culture , genetics , viral replication , gene , medicine , disease , pathology , infectious disease (medical specialty)

SARS-CoV-2 is a novel coronavirus currently causing a pandemic. Here, we performed a combined in-silico and cell culture comparison of SARS-CoV-2 and the closely related SARS-CoV.

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