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Novel approach for parallelizing pairwise comparison problems as applied to detecting segments identical by decent in whole-genome data
Author(s) -
Emmanuel Sapin,
Matthew C. Keller
Publication year - 2021
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btab084
Subject(s) - pairwise comparison , computer science , code (set theory) , biobank , source code , data mining , artificial intelligence , bioinformatics , biology , set (abstract data type) , programming language
Pairwise comparison problems arise in many areas of science. In genomics, datasets are already large and getting larger, and so operations that require pairwise comparisons-either on pairs of SNPs or pairs of individuals-are extremely computationally challenging. We propose a generic algorithm for addressing pairwise comparison problems that breaks a large problem (of order n2 comparisons) into multiple smaller ones (each of order n comparisons), allowing for massive parallelization.

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