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ConPlot: web-based application for the visualization of protein contact maps integrated with other data
Author(s) -
Filomeno Sánchez Rodríguez,
Shahram Mesdaghi,
Adam J. Simpkin,
J. Javier Burgos-Mármol,
David Murphy,
Ville Uski,
Ronan M. Keegan,
Daniel J. Rigden
Publication year - 2021
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btab049
Subject(s) - computer science , visualization , bespoke , documentation , inference , computer graphics (images) , data mining , web application , world wide web , information retrieval , programming language , artificial intelligence , political science , law
Covariance-based predictions of residue contacts and inter-residue distances are an increasingly popular data type in protein bioinformatics. Here we present ConPlot, a web-based application for convenient display and analysis of contact maps and distograms. Integration of predicted contact data with other predictions is often required to facilitate inference of structural features. ConPlot can therefore use the empty space near the contact map diagonal to display multiple coloured tracks representing other sequence-based predictions. Popular file formats are natively read and bespoke data can also be flexibly displayed. This novel visualization will enable easier interpretation of predicted contact maps.

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