ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment | Zendy

Diogo Borges Lima | Zendy; Mathieu Dupré | Zendy; Magalie Duchateau | Zendy; Quentin Giai Gianetto | Zendy; Martial Rey | Zendy; Mariette Matondo | Zendy; Julia ChamotRooke | Zendy

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ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment

Author(s) -

Diogo Borges Lima,

Mathieu Dupré,

Magalie Duchateau,

Quentin Giai Gianetto,

Martial Rey,

Mariette Matondo,

Julia ChamotRooke

Publication year - 2020

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btaa958

Subject(s) - computer science , identifier , software , visualization , shotgun , data mining , shotgun proteomics , information retrieval , proteomics , programming language , biology , biochemistry , gene

We present a high-performance software integrating shotgun with top-down proteomic data. The tool can deal with multiple experiments and search engines. Enable rapid and easy visualization, manual validation and comparison of the identified proteoform sequences including the post-translational modification characterization.

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